Do thermodynamic studies provide information on both the binding to and the activation of dopaminergic and other receptors?

BERNARD TESTA,*? PETER JENNER,$ GAVIN J. KILPATRICK,$ NABIL EL TAYAR,* HAN VAN DE WATERBEEMD* and C. DAVID MARSDENS * School of Pharmacy, University of Lausanne, CH-1005 Lausanne, Switzerland; and $ Medical Research Council Movement Disorder Research Group, University Department of Neurology and Parkinson’s Disease Society Research Centre, Institute of Psychiatry and King’s College Hospital Medical School. London SE5 8AF, U.K.